Fig. 1

Experimental design of the study. During acclimation period, dogs received nutritional supplement via syringe for training purpose. All animals were administered 5 mg/kg (dose volume 0.05 mL/kg) of the test articles via syringe directly in the dog’s mouth, at least 2 h before feeding in the morning. In Phase I & II, Group I and Group II animals received one of the test articles as shown