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Fig. 7 | Irish Veterinary Journal

Fig. 7

From: Reduction of microRNA-221 in BVDV infection enhances viral replication by targeting the ATG7-mediated autophagy pathway

Fig. 7

Mechanistic Model of the role of bta-miR-221 in Inhibiting BVDV Replication. This model illustrates the dual role of bta-miR-221 in the cellular response to BVDV infection. BVDV infection leads to a decrease in bta-miR-221 expression, consequently triggering the activation of the ATG7-LC3 autophagy pathway. This autophagic response potentially aids in the viral replication process. Conversely, bta-miR-221 inhibits BVDV replication within the cell, revealing a complex interplay among host miRNA regulation, autophagy, and viral replication dynamics. The diagram was created using FigDraw (https://www.figdraw.com/), providing a visual summary of the inhibitory mechanism of bta-miR-221 on BVDV replication through the modulation of cellular autophagy pathways

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Irish Veterinary Journal

ISSN: 2046-0481