Fig. 3
From: Canine circovirus: an emerging virus of dogs and wild canids
Following the inhalation of contaminated respiratory droplets and feces from an infected animal (A), viral replication occurs in crypt and lymphocyte cells. Subsequent to this event and the cessation of type I interferon production by the virus, we observe necrosis of intestinal crypt cells (B) in the animal, followed by clinical symptoms associated with the virus (Figure is created with BioRender)