Table 7 Cut-off points, sensitivity, specificity, LR, PPV, NPV, accuracy rate and percentages of increase or decrease in the estimated cytokines and oxidative stress markers in the PG compared with those in the CG
Parameters | Cut-off | Sensitivity | Specificity | PPV | NPV | LR | AR | % of increase or decrease |
|---|---|---|---|---|---|---|---|---|
IL-1α (Pg/ml) | 29.50 | 100% | 90% | 93.75% | 100% | 10 | 96% | 298.38% |
IL-1β (Pg/ml) | 28.50 | 100% | 85% | 90.91% | 100% | 6.6 | 94% | 281.34% |
IL-6 (Pg/ml) | 28.50 | 100% | 90% | 93.75% | 100% | 10 | 96% | 250.63% |
TNF-α (Pg/ml) | 28.50 | 100% | 90% | 93.75% | 100% | 10 | 96% | 251.02% |
IL-10 (Pg/ml) | 100.80 | 100% | 80% | 88.24% | 100% | 5 | 92% | −12.57% |
MDA (nmol/ml) | 14.10 | 100% | 80% | 88.24% | 100% | 5 | 92% | 83.01% |
NO (µmol/L) | 27.50 | 100% | 60% | 78.95% | 100% | 2.5 | 84% | 20.63% |
CAT (U/L) | 392.50 | 100% | 90% | 93.75% | 100% | 10 | 96% | −29.85% |
GPx (mU/L) | 1012.00 | 100% | 90% | 93.75% | 100% | 10 | 96% | −26.81% |
GR (ng/ml) | 7.59 | 100% | 80% | 88.24% | 100% | 5 | 92% | −36.69% |